mouse MYSM1 shRNA silencing AAV

Name 
AAV-m-MYSM1-shRNA
Cat No 
shAAV-265370
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Mysm1.

shAAV-265370
AAV-m-MYSM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mysm1 (myb-like, SWIRM and MPN domains 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C130067A03Rik; C530050H10Rik
Description (Vector)
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
Gene ID
320713
Gene Name (Vector)
myb-like, SWIRM and MPN domains 1
Gene Symbol
Mysm1
ORF Size (aa)
2460
ORF Size (bp)
2460 bp
RefSeq ID
NM_177239
RefSeq Synonyms
NM_177239, BC151172, BC150946,
Species
mouse
UniGene ID
Mm.468748

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.