mouse MYO1E shRNA silencing AAV

Name 
AAV-m-MYO1E-shRNA
Cat No 
shAAV-265331
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Myo1e.

shAAV-265331
AAV-m-MYO1E-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Myo1e (myosin IE). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310020N23Rik; 9130023P14Rik; AA407778; myosin-1e; myr 3
Description (Vector)
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via C11orf46/ ARF7EP and ARL14.
Gene ID
71602
Gene Name (Vector)
myosin IE
Gene Symbol
Myo1e
ORF Size (aa)
3324
ORF Size (bp)
3324 bp
RefSeq ID
NM_181072
RefSeq Synonyms
NM_181072, BC051391,
Species
mouse
UniGene ID
Mm.249311

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.