mouse MUTYH shRNA silencing AAV

Name 
AAV-m-MUTYH-shRNA
Cat No 
shAAV-265223
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Mutyh.

shAAV-265223
AAV-m-MUTYH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mutyh (mutY DNA glycosylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5730495A01Rik; Mutyha; Mutyhalpha; Mutyhb; Mutyhbeta; Mutyhc; Myh
Description (Vector)
Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.
Gene ID
70603
Gene Name (Vector)
mutY DNA glycosylase
Gene Symbol
Mutyh
ORF Size (aa)
1548
ORF Size (bp)
1548 bp
RefSeq ID
NM_133250
RefSeq Synonyms
NM_133250, NM_001316747, NM_001159581, BC057942,
Species
mouse
UniGene ID
Mm.180333

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.