mouse MUL1 shRNA silencing AAV

Name
AAV-m-MUL1-shRNA

Cat No
shAAV-265196

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Mul1.

shAAV-265196

AAV-m-MUL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mul1 (mitochondrial ubiquitin ligase activator of NFKB 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

0610009K11Rik; AV000801; Gide

Description (Vector)

Exhibits weak E3 ubiquitin-protein ligase activity, but preferentially acts as a SUMO E3 ligase at physiological concentrations. Plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Gene ID

68350

Gene Name (Vector)

mitochondrial ubiquitin ligase activator of NFKB 1

Gene Symbol

Mul1

ORF Size (aa)

1059

ORF Size (bp)

1059 bp

RefSeq ID

NM_026689

RefSeq Synonyms

NM_026689, BC019516,

Species

mouse

UniGene ID

Mm.103413

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.