mouse MTBP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mtbp.
shAAV-265108
AAV-m-MTBP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mtbp (Mdm2, transformed 3T3 cell double minute p53 binding protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI429604; MDM2BP
Description (Vector)
Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.
Gene ID
105837
Gene Name (Vector)
Mdm2, transformed 3T3 cell double minute p53 binding protein
Gene Symbol
Mtbp
ORF Size (aa)
2685
ORF Size (bp)
2685 bp
RefSeq ID
NM_134092
RefSeq Synonyms
NM_134092, NM_001168250, BC052197,
Species
mouse
UniGene ID
Mm.390829
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.