mouse MRGPRD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mrgprd.
shAAV-264884
AAV-m-MRGPRD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mrgprd (MAS-related GPR, member D). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Gm499; Mgrd; MrgD; TGR7
Description (Vector)
MRGPRD may regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
Gene ID
211578
Gene Name (Vector)
MAS-related GPR, member D
Gene Symbol
Mrgprd
ORF Size (aa)
966
ORF Size (bp)
966 bp
RefSeq ID
NM_203490
RefSeq Synonyms
NM_203490, BC137950, BC137948,
Species
mouse
UniGene ID
Mm.370299
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.