mouse MMP17 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mmp17.
shAAV-264724
AAV-m-MMP17-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mmp17 (matrix metallopeptidase 17). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MT4-MMP; MT4MMP; MTMMP4
Description (Vector)
Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Gene ID
23948
Gene Name (Vector)
matrix metallopeptidase 17
Gene Symbol
Mmp17
ORF Size (aa)
1737
ORF Size (bp)
1737 bp
RefSeq ID
NM_011846
RefSeq Synonyms
NM_011846, BC051917,
Species
mouse
UniGene ID
Mm.42047
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.