mouse MMEL1 shRNA silencing AAV

Name 
AAV-m-MMEL1-shRNA
Cat No 
shAAV-264710
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Mmel1.

shAAV-264710
AAV-m-MMEL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mmel1 (membrane metallo-endopeptidase-like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Mell1; NEP2; NEPII; Nl1; SEP
Description (Vector)
Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificiy with MME and cleaves peptides at the same amide bond (By similarity).
Gene ID
27390
Gene Name (Vector)
membrane metallo-endopeptidase-like 1
Gene Symbol
Mmel1
ORF Size (aa)
2229
ORF Size (bp)
2229 bp
RefSeq ID
NM_013783
RefSeq Synonyms
NM_013783, BC144804, BC137649,
Species
mouse
UniGene ID
Mm.116944

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.