mouse MGMT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mgmt.
shAAV-264608
AAV-m-MGMT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mgmt (O-6-methylguanine-DNA methyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Agat; AGT; AI267024
Description (Vector)
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Gene ID
17314
Gene Name (Vector)
O-6-methylguanine-DNA methyltransferase
Gene Symbol
Mgmt
ORF Size (aa)
636
RefSeq ID
NM_008598
RefSeq Synonyms
NM_008598, BC096557, BC031888,
Species
mouse
UniGene ID
Mm.440219
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.