mouse MESP2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mesp2.
shAAV-264507
AAV-m-MESP2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mesp2 (mesoderm posterior 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHc6
Description (Vector)
Transcription factor with important role in somitogenesis. Defines the rostrocaudal patterning of the somite by participating in distinct Notch pathways. Regulates also the FGF signaling pathway. Specifies the rostral half of the somites. Generates rostro-caudal polarity of somites by down-regulating in the presumptive rostral domain DLL1, a Notch ligand. Participates in the segment border formation by activating in the anterior presomitic mesoderm LFNG, a negative regulator of DLL1-Notch signaling. Acts as a strong suppressor of Notch activity. Together with MESP1 is involved in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.
Gene ID
17293
Gene Name (Vector)
mesoderm posterior 2
Gene Symbol
Mesp2
ORF Size (aa)
1113
RefSeq ID
NM_008589
RefSeq Synonyms
NM_008589, BC145654, BC145652,
Species
mouse
UniGene ID
Mm.31472
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.