mouse MESDC2 shRNA silencing AAV

Name 
AAV-m-MESDC2-shRNA
Cat No 
shAAV-264504
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Mesdc2.

shAAV-264504
AAV-m-MESDC2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mesdc2 (mesoderm development candidate 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2210015O11Rik; AW537813; mesd; mKIAA0081; msd
Description (Vector)
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.
Gene ID
67943
Gene Name (Vector)
mesoderm development candidate 2
Gene Symbol
Mesdc2
ORF Size (aa)
516
ORF Size (bp)
516 bp
RefSeq ID
NM_023403
RefSeq Synonyms
NM_023403, BC014742,
Species
mouse
UniGene ID
Mm.117365

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.