mouse MAPK4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Mapk4.
shAAV-264221
AAV-m-MAPK4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Mapk4 (mitogen-activated protein kinase 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A330097D03Rik; Erk3; p63Mapk; Prkm4
Description (Vector)
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).
Gene ID
225724
Gene Name (Vector)
mitogen-activated protein kinase 4
Gene Symbol
Mapk4
ORF Size (aa)
1752
ORF Size (bp)
1752 bp
RefSeq ID
NM_172632
RefSeq Synonyms
NM_172632, BC062911, BC058942,
Species
mouse
UniGene ID
Mm.254517
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.