mouse LONP2 shRNA silencing AAV

Name 
AAV-m-LONP2-shRNA
Cat No 
shAAV-263751
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Lonp2.

shAAV-263751
AAV-m-LONP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Lonp2 (lon peptidase 2, peroxisomal). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1300002A08Rik; AU015403; Lonp
Description (Vector)
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import (By similarity). May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.
Gene ID
66887
Gene Name (Vector)
lon peptidase 2, peroxisomal
Gene Symbol
Lonp2
ORF Size (aa)
2559
ORF Size (bp)
2559 bp
RefSeq ID
NM_025827
RefSeq Synonyms
NM_025827, NM_001168591, BC049090,
Species
mouse
UniGene ID
Mm.324550

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.