mouse SH3BP1 shRNA silencing AAV

Name 
AAV-m-SH3BP1-shRNA
Cat No 
shAAV-263747
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Sh3bp1.

shAAV-263747
AAV-m-SH3BP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Sh3bp1 (SH3-domain binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3BP-1
Description (Vector)
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).
Gene ID
20401
Gene Name (Vector)
SH3-domain binding protein 1
Gene Symbol
Sh3bp1
ORF Size (aa)
1803
ORF Size (bp)
1803 bp
RefSeq ID
NM_009164
RefSeq Synonyms
NM_009164, NM_001316686, NM_001316685, NM_001316684, BC004598,
Species
mouse
UniGene ID
Mm.4462

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.