mouse KMO shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Kmo.
shAAV-263028
AAV-m-KMO-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Kmo (kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI046660
Description (Vector)
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.
Gene ID
98256
Gene Name (Vector)
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Gene Symbol
Kmo
ORF Size (aa)
1440
ORF Size (bp)
1440 bp
RefSeq ID
NM_133809
RefSeq Synonyms
NM_133809, BC014683,
Species
mouse
UniGene ID
Mm.27217
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.