mouse KHDRBS2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Khdrbs2.
shAAV-262784
AAV-m-KHDRBS2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Khdrbs2 (KH domain containing, RNA binding, signal transduction associated 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6330586C16Rik; Slim1; Slm1
Description (Vector)
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity).
Gene ID
170771
Gene Name (Vector)
KH domain containing, RNA binding, signal transduction associated 2
Gene Symbol
Khdrbs2
ORF Size (aa)
1050
RefSeq ID
NM_133235
RefSeq Synonyms
NM_133235, BC132119, BC132117,
Species
mouse
UniGene ID
Mm.336594
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.