mouse KCTD13 shRNA silencing AAV

Name
AAV-m-KCTD13-shRNA

Cat No
shAAV-262728

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Kctd13.

shAAV-262728

AAV-m-KCTD13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Kctd13 (potassium channel tetramerisation domain containing 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1500003N18Rik; AV259508; Pdip1; PDIP1alpha; Poldip1

Description (Vector)

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.

Gene ID

233877

Gene Name (Vector)

potassium channel tetramerisation domain containing 13

Gene Symbol

Kctd13

ORF Size (aa)

990

RefSeq ID

NM_172747

RefSeq Synonyms

NM_172747, BC079607,

Species

mouse

UniGene ID

Mm.245897

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.