mouse KCNN2 shRNA silencing AAV

Name 
AAV-m-KCNN2-shRNA
Cat No 
shAAV-262697
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Kcnn2.

shAAV-262697
AAV-m-KCNN2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Kcnn2 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bc; fri; KCa2.2; SK2; SKCA2
Description (Vector)
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
Gene ID
140492
Gene Name (Vector)
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Gene Symbol
Kcnn2
ORF Size (aa)
1725
ORF Size (bp)
1725 bp
RefSeq ID
NM_080465
RefSeq Synonyms
NM_080465, NM_001312905, BC137656, BC125475,
Species
mouse
UniGene ID
Mm.458654

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.