mouse KCNJ6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Kcnj6.
shAAV-262669
AAV-m-KCNJ6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Kcnj6 (potassium inwardly-rectifying channel, subfamily J, member 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BIR1; GIRK2; KATP2; KCNJ7; Kir3.2; weaver; wv
Description (Vector)
This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Gene ID
16522
Gene Name (Vector)
potassium inwardly-rectifying channel, subfamily J, member 6
Gene Symbol
Kcnj6
ORF Size (aa)
1278
ORF Size (bp)
1278 bp
RefSeq ID
NM_010606
RefSeq Synonyms
NM_010606, NM_001025590, NM_001025585, NM_001025584, BC125565, BC120794,
Species
mouse
UniGene ID
Mm.328720
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.