mouse JPH4 shRNA silencing AAV

Name
AAV-m-JPH4-shRNA

Cat No
shAAV-262534

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Jph4.

shAAV-262534

AAV-m-JPH4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Jph4 (junctophilin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

9330157P13Rik; JP-4; JPHL1

Description (Vector)

Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain-specific and appears to have an active role in certain neurons involved in motor coordination and memory (By similarity).

Gene ID

319984

Gene Name (Vector)

junctophilin 4

Gene Symbol

Jph4

ORF Size (aa)

1887

ORF Size (bp)

1887 bp

RefSeq ID

NM_177049

RefSeq Synonyms

NM_177049, BC052722, BC052376, BC052049,

Species

mouse

UniGene ID

Mm.19047

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.