mouse ITGB1BP3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Nmrk2.
shAAV-262449
AAV-m-ITGB1BP3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Nmrk2 (nicotinamide riboside kinase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310015C21Rik; Itgb1bp3; Mibp
Description (Vector)
Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis.
Gene ID
69564
Gene Name (Vector)
nicotinamide riboside kinase 2
Gene Symbol
Nmrk2
ORF Size (aa)
588
ORF Size (bp)
588 bp
RefSeq ID
NM_027120
RefSeq Synonyms
NM_027120, BC119246, BC119244,
Species
mouse
UniGene ID
Mm.437211
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.