mouse ITGAV shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Itgav.
shAAV-262444
AAV-m-ITGAV-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Itgav (integrin alpha V). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110004F14Rik; 2610028E01Rik; CD51; D430040G12Rik
Description (Vector)
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Gene ID
16410
Gene Name (Vector)
integrin alpha V
Gene Symbol
Itgav
ORF Size (aa)
3135
ORF Size (bp)
3135 bp
RefSeq ID
NM_008402
RefSeq Synonyms
NM_008402, BC167182,
Species
mouse
UniGene ID
Mm.227
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.