mouse ITGAM shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Itgam.
shAAV-262443
AAV-m-ITGAM-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Itgam (integrin alpha M). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cd11b; CD11b/CD18; CR3; CR3A; F730045J24Rik; Ly-40; Mac-1; Mac-1a; MAC1
Description (Vector)
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Gene ID
16409
Gene Name (Vector)
integrin alpha M
Gene Symbol
Itgam
ORF Size (aa)
3459
ORF Size (bp)
3459 bp
RefSeq ID
NM_008401
RefSeq Synonyms
NM_008401, NM_001082960, BC156991, BC156094,
Species
mouse
UniGene ID
Mm.262106
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.