mouse INTS12 shRNA silencing AAV

Name 
AAV-m-INTS12-shRNA
Cat No 
shAAV-262291
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ints12.

shAAV-262291
AAV-m-INTS12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ints12 (integrator complex subunit 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110020M19Rik; 2810027J24Rik; 4930529N21Rik; A230056J18Rik; AI666778; int12; Phf22
Description (Vector)
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
Gene ID
71793
Gene Name (Vector)
integrator complex subunit 12
Gene Symbol
Ints12
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
RefSeq ID
NM_027927
RefSeq Synonyms
NM_027927, BC046996, BC023801,
Species
mouse
UniGene ID
Mm.246726

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.