mouse IL23A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Il23a.
shAAV-262159
AAV-m-IL23A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Il23a (interleukin 23, alpha subunit p19). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IL-23; p19
Description (Vector)
Associates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Gene ID
83430
Gene Name (Vector)
interleukin 23, alpha subunit p19
Gene Symbol
Il23a
ORF Size (aa)
591
ORF Size (bp)
591 bp
RefSeq ID
NM_031252
RefSeq Synonyms
NM_031252, BC019953,
Species
mouse
UniGene ID
Mm.125482
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.