mouse IL1RN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Il1rn.
shAAV-262146
AAV-m-IL1RN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Il1rn (interleukin 1 receptor antagonist). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
F630041P17Rik; IL-1ra
Description (Vector)
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
Gene ID
16181
Gene Name (Vector)
interleukin 1 receptor antagonist
Gene Symbol
Il1rn
ORF Size (aa)
480
RefSeq ID
NM_031167
RefSeq Synonyms
NM_031167, NM_001159562, NM_001039701, BC042532,
Species
mouse
UniGene ID
Mm.882
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.