mouse IL12RB1 shRNA silencing AAV

Name 
AAV-m-IL12RB1-shRNA
Cat No 
shAAV-262100
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Il12rb1.

shAAV-262100
AAV-m-IL12RB1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Il12rb1 (interleukin 12 receptor, beta 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD212; IL-12R[b]
Description (Vector)
Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Gene ID
16161
Gene Name (Vector)
interleukin 12 receptor, beta 1
Gene Symbol
Il12rb1
ORF Size (aa)
2007
ORF Size (bp)
2007 bp
RefSeq ID
NM_008353
RefSeq Synonyms
NM_008353, BC057212,
Species
mouse
UniGene ID
Mm.731

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.