mouse IGF1 shRNA silencing AAV

Name 
AAV-m-IGF1-shRNA
Cat No 
shAAV-261962
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse IGF1.

shAAV-261962
AAV-m-IGF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse IGF1 (insulin-like growth factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C730016P09Rik; Igf-1; Igf-I
Description (Vector)
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.
Gene ID
16000
Gene Name (Vector)
insulin-like growth factor 1
Gene Symbol
IGF1
ORF Size (aa)
402
RefSeq ID
NM_010512
RefSeq Synonyms
NM_184052, NM_010512, NM_001314010, NM_001111276, NM_001111275, NM_001111274, BC012409,
Species
mouse
UniGene ID
Mm.268521

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.