mouse IFITM2 shRNA silencing AAV

Name 
AAV-m-IFITM2-shRNA
Cat No 
shAAV-261893
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ifitm2.

shAAV-261893
AAV-m-IFITM2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ifitm2 (interferon induced transmembrane protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DSPA2c; fragilis3; Ifitm3l; mil-3
Description (Vector)
IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
Gene ID
80876
Gene Name (Vector)
interferon induced transmembrane protein 2
Gene Symbol
Ifitm2
ORF Size (aa)
435
RefSeq ID
NM_030694
RefSeq Synonyms
NM_030694, BC084679, BC002160, BC002102,
Species
mouse
UniGene ID
Mm.379266

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.