mouse ICAM1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Icam1.
shAAV-261824
AAV-m-ICAM1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Icam1 (intercellular adhesion molecule 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD54; Icam-1; Ly-47; MALA-2
Description (Vector)
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Gene ID
15894
Gene Name (Vector)
intercellular adhesion molecule 1
Gene Symbol
Icam1
ORF Size (aa)
1614
ORF Size (bp)
1614 bp
RefSeq ID
NM_010493
RefSeq Synonyms
NM_010493, BC008626,
Species
mouse
UniGene ID
Mm.435508
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.