mouse HSP90AB1 shRNA silencing AAV

Cat. No: shAAV-261727

Availability: 4-5 weeks

Name: AAV-m-HSP90AB1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Hsp90ab1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Hsp90ab1
Gene Name: heat shock protein 90 alpha (cytosolic), class B member 1
Gene ID: 15516
Gene Synonyms: 90kDa; AL022974; C81438; Hsp84; Hsp84-1; Hsp90; Hspcb
ORF Size: 2175 bp
RefSeq#: NM_008302
Gene Description: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
UniGene ID: Mm.2180