mouse HSD17B10 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Hsd17b10.
shAAV-261695
AAV-m-HSD17B10-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Hsd17b10 (hydroxysteroid (17-beta) dehydrogenase 10). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
17bHSD10; Ads9; ERAB; Hadh2
Description (Vector)
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
Gene ID
15108
Gene Name (Vector)
hydroxysteroid (17-beta) dehydrogenase 10
Gene Symbol
Hsd17b10
ORF Size (aa)
786
ORF Size (bp)
786 bp
RefSeq ID
NM_016763
RefSeq Synonyms
NM_016763, BC027517,
Species
mouse
UniGene ID
Mm.6994
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.