mouse HP shRNA silencing AAV

Name
AAV-m-HP-shRNA

Cat No
shAAV-261624

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Hp.

shAAV-261624

AAV-m-HP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Hp (haptoglobin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HP-1; preHP2

Description (Vector)

Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes|Function: Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.

Gene ID

15439

Gene Name (Vector)

haptoglobin

Gene Symbol

ORF Size (aa)

1044

ORF Size (bp)

1044 bp

RefSeq ID

NM_017370

RefSeq Synonyms

NM_017370, NM_001329965, BC138872,

Species

mouse

UniGene ID

Mm.26730

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.