mouse HOOK3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Hook3.
shAAV-261555
AAV-m-HOOK3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Hook3 (hook microtubule tethering protein 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5830454D03Rik; AI317159; E330005F07Rik
Description (Vector)
Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex.
Gene ID
320191
Gene Name (Vector)
hook microtubule tethering protein 3
Gene Symbol
Hook3
ORF Size (aa)
2163
ORF Size (bp)
2163 bp
RefSeq ID
NM_207659
RefSeq Synonyms
NM_207659, BC090960,
Species
mouse
UniGene ID
Mm.458186
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.