mouse HOMER2 shRNA silencing AAV

Name 
AAV-m-HOMER2-shRNA
Cat No 
shAAV-261547
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Homer2.

shAAV-261547
AAV-m-HOMER2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Homer2 (homer scaffolding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9330120H11Rik; AW539445; CPD; Vesl-2
Description (Vector)
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.
Gene ID
26557
Gene Name (Vector)
homer scaffolding protein 2
Gene Symbol
Homer2
ORF Size (aa)
1062
ORF Size (bp)
1062 bp
RefSeq ID
NM_011983
RefSeq Synonyms
NM_011983, NM_001164087, NM_001164086, BC153023, BC148402,
Species
mouse
UniGene ID
Mm.228

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.