mouse HLTF shRNA silencing AAV

Name
AAV-m-HLTF-shRNA

Cat No
shAAV-261433

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse HLTF.

shAAV-261433

AAV-m-HLTF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse HLTF (helicase-like transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AF010600; BC057116; P113; Smarca3; Snf2l3;

Description (Vector)

Has both helicasee and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.

Gene ID

20585

Gene Name (Vector)

helicase-like transcription factor

Gene Symbol

HLTF

ORF Size (aa)

3012

ORF Size (bp)

3012 bp

RefSeq ID

NM_009210

RefSeq Synonyms

NM_144959, NM_009210, BC059240, BC057116,

Species

mouse

UniGene ID

Mm.209650

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.