mouse HIST2H2BE shRNA silencing AAV

Name
AAV-m-HIST2H2BE-shRNA

Cat No
shAAV-261403

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Hist2h2be.

shAAV-261403

AAV-m-HIST2H2BE-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Hist2h2be (histone cluster 2, H2be). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AV127319; H2b-613; T25626

Description (Vector)

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling|Function: Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

Gene ID

319190

Gene Name (Vector)

histone cluster 2, H2be

Gene Symbol

Hist2h2be

ORF Size (aa)

381

RefSeq ID

NM_178214

RefSeq Synonyms

NM_178214, BC047137,

Species

mouse

UniGene ID

Mm.439791

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.