mouse HIP1 shRNA silencing AAV

Name
AAV-m-HIP1-shRNA

Cat No
shAAV-261304

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Hip1.

shAAV-261304

AAV-m-HIP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Hip1 (huntingtin interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2610109B09Rik; A930014B11Rik; E130315I21Rik; mKIAA4113

Description (Vector)

Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors.

Gene ID

215114

Gene Name (Vector)

huntingtin interacting protein 1

Gene Symbol

Hip1

ORF Size (aa)

2721

ORF Size (bp)

2721 bp

RefSeq ID

NM_146001

RefSeq Synonyms

NM_146001, BC017516,

Species

mouse

UniGene ID

Mm.280805

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.