mouse HDAC5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Hdac5.
shAAV-261178
AAV-m-HDAC5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Hdac5 (histone deacetylase 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI426555; Hdac4; mHDA1; mKIAA0600
Description (Vector)
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.
Gene ID
15184
Gene Name (Vector)
histone deacetylase 5
Gene Symbol
Hdac5
ORF Size (aa)
3345
ORF Size (bp)
3345 bp
RefSeq ID
NM_010412
RefSeq Synonyms
NM_010412, NM_001284250, NM_001284249, NM_001284248, NM_001077696, BC060609,
Species
mouse
UniGene ID
Mm.22665
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.