mouse GTF2IRD1 shRNA silencing AAV

Name
AAV-m-GTF2IRD1-shRNA

Cat No
shAAV-260890

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Gtf2ird1.

shAAV-260890

AAV-m-GTF2IRD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Gtf2ird1 (general transcription factor II I repeat domain-containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1700012P16Rik; BEN; Cream1; ESTM9; Gtf2il; GTF3; MusTRD1; Tg(Alb1-Myc)166.8Sst; WBSCR11; X83320

Description (Vector)

GTF2IRD1 may be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity).

Gene ID

57080

Gene Name (Vector)

general transcription factor II I repeat domain-containing 1

Gene Symbol

Gtf2ird1

ORF Size (aa)

3138

ORF Size (bp)

3138 bp

RefSeq ID

NM_020331

RefSeq Synonyms

NM_020331, NM_001347488, NM_001244936, NM_001081470, NM_001081469, NM_001081468, NM_001081467, NM_001081466, NM_001081465, NM_001081464, NM_001081463, NM_001081462, BC083150, BC058964, BC057091, BC050822,

Species

mouse

UniGene ID

Mm.332735

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.