mouse GPR68 shRNA silencing AAV

Name 
AAV-m-GPR68-shRNA
Cat No 
shAAV-260656
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Gpr68.

shAAV-260656
AAV-m-GPR68-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Gpr68 (G protein-coupled receptor 68). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BB131428; Ogr1
Description (Vector)
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity).
Gene ID
238377
Gene Name (Vector)
G protein-coupled receptor 68
Gene Symbol
Gpr68
ORF Size (aa)
1098
ORF Size (bp)
1098 bp
RefSeq ID
NM_175493
RefSeq Synonyms
NM_175493, NM_001177674, NM_001177673, BC118044, BC118034,
Species
mouse
UniGene ID
Mm.32160

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.