mouse GLRB shRNA silencing AAV

Name 
AAV-m-GLRB-shRNA
Cat No 
shAAV-260200
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Glrb.

shAAV-260200
AAV-m-GLRB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Glrb (glycine receptor, beta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI853901; Glyrb; spa; spastic
Description (Vector)
The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
Gene ID
14658
Gene Name (Vector)
glycine receptor, beta subunit
Gene Symbol
Glrb
ORF Size (aa)
1491
ORF Size (bp)
1491 bp
RefSeq ID
NM_010298
RefSeq Synonyms
NM_010298, NM_001345996, NM_001345959, NM_001345958, NM_001345957, NM_001345956, NM_001345955, NM_001281969, BC037605,
Species
mouse
UniGene ID
Mm.275639

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.