mouse GHR shRNA silencing AAV

Name 
AAV-m-GHR-shRNA
Cat No 
shAAV-260086
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse GHR.

shAAV-260086
AAV-m-GHR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse GHR (growth hormone receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GHBP; GHR/BP
Description (Vector)
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity)|Function: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling|Function: Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
Gene ID
14600
Gene Name (Vector)
growth hormone receptor
Gene Symbol
GHR
ORF Size (aa)
1953
ORF Size (bp)
1953 bp
RefSeq ID
NM_010284
RefSeq Synonyms
NM_010284, NM_001286370, NM_001048178, NM_001048147, BC075720,
Species
mouse
UniGene ID
Mm.3986

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.