mouse GGT1 shRNA silencing AAV

Name 
AAV-m-GGT1-shRNA
Cat No 
shAAV-260076
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ggt1.

shAAV-260076
AAV-m-GGT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ggt1 (gamma-glutamyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD224; dwg; GGT; GGT 1; GGT-1; Ggtp
Description (Vector)
Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive.
Gene ID
14598
Gene Name (Vector)
gamma-glutamyltransferase 1
Gene Symbol
Ggt1
ORF Size (aa)
1707
ORF Size (bp)
1707 bp
RefSeq ID
NM_008116
RefSeq Synonyms
NM_008116, NM_001305992, BC012969,
Species
mouse
UniGene ID
Mm.4559

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.