mouse GADD45GIP1 shRNA silencing AAV

Name 
AAV-m-GADD45GIP1-shRNA
Cat No 
shAAV-259830
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Gadd45gip1.

shAAV-259830
AAV-m-GADD45GIP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Gadd45gip1 (growth arrest and DNA-damage-inducible, gamma interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310040G17Rik; AI425883; Crif1; MRP-L59; Plinp1
Description (Vector)
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
Gene ID
102060
Gene Name (Vector)
growth arrest and DNA-damage-inducible, gamma interacting protein 1
Gene Symbol
Gadd45gip1
ORF Size (aa)
669
ORF Size (bp)
669 bp
RefSeq ID
NM_183358
RefSeq Synonyms
NM_183358, BC061069,
Species
mouse
UniGene ID
Mm.255539

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.