mouse FKBP1A shRNA silencing AAV

Name
AAV-m-FKBP1A-shRNA

Cat No
shAAV-259446

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Fkbp1a.

shAAV-259446

AAV-m-FKBP1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fkbp1a (FK506 binding protein 1a). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Fkbp; Fkbp1; FKBP12

Description (Vector)

Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Gene ID

14225

Gene Name (Vector)

FK506 binding protein 1a

Gene Symbol

Fkbp1a

ORF Size (aa)

327

RefSeq ID

NM_008019

RefSeq Synonyms

NM_008019, NM_001302080, NM_001302079, NM_001302078, NM_001302077, BC004671,

Species

mouse

UniGene ID

Mm.381214

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.