mouse FIG4 shRNA silencing AAV

Name
AAV-m-FIG4-shRNA

Cat No
shAAV-259423

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Fig4.

shAAV-259423

AAV-m-FIG4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fig4 (FIG4 phosphoinositide 5-phosphatase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A530089I17Rik; AI326867; Sac3

Description (Vector)

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide substrates in the order PtdIns(4,5)P2 > PtdIns(3,5)P2 > PtdIns(3,4,5)P3. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.

Gene ID

103199

Gene Name (Vector)

FIG4 phosphoinositide 5-phosphatase

Gene Symbol

Fig4

ORF Size (aa)

2724

ORF Size (bp)

2724 bp

RefSeq ID

NM_133999

RefSeq Synonyms

NM_133999, BC031887, BC015295,

Species

mouse

UniGene ID

Mm.277242

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.