mouse FCER1A shRNA silencing AAV

Name 
AAV-m-FCER1A-shRNA
Cat No 
shAAV-259280
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Fcer1a.

shAAV-259280
AAV-m-FCER1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fcer1a (Fc receptor, IgE, high affinity I, alpha polypeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Fce1a; fcepsilonri; FcERI; Fcr-5
Description (Vector)
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Gene ID
14125
Gene Name (Vector)
Fc receptor, IgE, high affinity I, alpha polypeptide
Gene Symbol
Fcer1a
ORF Size (aa)
753
ORF Size (bp)
753 bp
RefSeq ID
NM_010184
RefSeq Synonyms
NM_010184, BC125457, BC125455,
Species
mouse
UniGene ID
Mm.5266

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.