mouse FBXO45 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fbxo45.
shAAV-259247
AAV-m-FBXO45-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fbxo45 (F-box protein 45). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610017J04Rik; AI463119; BC026799
Description (Vector)
Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Plays a role in the regulation of neurotransmission at mature neurons (By similarity). May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway (By similarity). Specifically recognizes TP73, promoting its ubiquitination and degradation.
Gene ID
268882
Gene Name (Vector)
F-box protein 45
Gene Symbol
Fbxo45
ORF Size (aa)
861
ORF Size (bp)
861 bp
RefSeq ID
NM_173439
RefSeq Synonyms
NM_173439, BC098203, BC088738, BC026799,
Species
mouse
UniGene ID
Mm.256137
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.