mouse FBXL5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fbxl5.
shAAV-259214
AAV-m-FBXL5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fbxl5 (F-box and leucine-rich repeat protein 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Fbl4; Fir4
Description (Vector)
Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
Gene ID
242960
Gene Name (Vector)
F-box and leucine-rich repeat protein 5
Gene Symbol
Fbxl5
ORF Size (aa)
2055
ORF Size (bp)
2055 bp
RefSeq ID
NM_178729
RefSeq Synonyms
NM_178729, NM_001159963, BC113798, BC047214,
Species
mouse
UniGene ID
Mm.25794
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.